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Antidepressants

Asked by Mark PritchardConservativeDepartment of Health and Social CareTabled Answered 17 February 2025UIN 28906

The question

To ask the Secretary of State for Health and Social Care, if he will take steps with NHS England to review the (a) volume and (b) type of antidepressants prescribed on the NHS and their (i) side effects, (ii) long-term effectiveness and (iii) addictiveness.

Answered by Karin Smyth

The National Institute of Care and Excellence (NICE) and Medicines and Healthcare products Regulatory Agency (MHRA) are the relevant regulatory bodies in this area. While antidepressants can be helpful for some patients, NICE guidance recommends a range of non-drug options that should be considered first for people who present with less severe mental health conditions.

For patients diagnosed with depression, antidepressants are an effective treatment method. NICE has produced guidelines on antidepressants, which are available at the following link:

https://www.nice.org.uk/guidance/ng222/resources/depression-in-adults-treatment-and-management-pdf-66143832307909

To ensure antidepressant drugs are made available to patients only where the benefits outweigh the potential harms, NHS England is encouraging integrated care boards to address inappropriate antidepressant prescribing and to consider commissioning services for patients wishing to reduce or stop antidepressants.

MHRA is leading a project to improve the information supplied with dependency-forming medicines. The project aims to improve risk minimisation measures and better inform and educate healthcare professionals and patients about the risk of dependence, addiction, tolerance, and withdrawal related to a wide range of medicines, including antidepressants in the United Kingdom.

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