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Pancreatic Enzyme Replacement Therapy: Shortages

Asked by Alicia KearnsConservativeDepartment of Health and Social CareTabled Answered 3 March 2025UIN 33088

The question

To ask the Secretary of State for Health and Social Care, what steps he is taking to help tackle the shortage of pancreatic enzyme replacement therapy drugs.

Answered by Karin Smyth

The Department is continuing to engage with all suppliers of pancreatic enzyme replacement therapy (PERT) to boost production to mitigate the supply issue. Suppliers have managed to secure additional pharmaceutical ingredients resulting in expected increased volumes of PERT for 2025. The Department has also reached out to specialist importers who have sourced unlicensed stock to assist in covering the gap in the market. In December 2024, the Department issued further management advice to healthcare professionals. This directs clinicians to consider these unlicensed imports when licensed stock is unavailable and includes actions for integrated care boards to ensure local mitigation plans are put in place and implemented. The Department, in collaboration with NHS England, has created a webpage to include the latest updates on PERT availability and easily accessible advice on the prescribing and ordering of alternative PERT products.

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