Sepsis: Databases

The Government understands the clear need for reliable data on sepsis. Currently, the Office for National Statistics publishes data on the number of death registrations where sepsis was the underlying cause of death, and where sepsis was mentioned anywhere on the death certificate, in England and Wales between 2001 and 2023. However, there is a lack of accurate estimates of incidence and prevalence of sepsis cases due to inconsistency in the definitions used to describe sepsis, and differences in coding between professionals and organisations in the United Kingdom.

A sepsis registry would use retrospective data collection. The Government is, instead, focusing on improving our understanding of the current prevalence of infections and suspected sepsis, including the up-to-date burden to the National Health Service. The Department is working with NHS England and the UK Health Security Agency to monitor trends in infection incidence and the infection burden in secondary care, which are complex, multifactorial issues.