Antidepressants: Prescriptions

Antidepressants can be an effective treatment option for depression when prescribed safely and in alignment with patient preferences. They are also used in anxiety and chronic pain.

It is for the responsible clinician to work with their patient to decide on the best course of treatment, with the provision of the most clinically appropriate care for the patient always being the primary consideration. It is important for patients to be able to make informed choices about whether to take antidepressants, and NHS England has recently published a Patient Decision Aid on this topic, produced by the National Institute for Health and Care Excellence (NICE).

It is also important for clinicians to recognise that, while antidepressants may be helpful for some patients, non-drug options are likely to be a better option for most people who present with less severe mental health conditions. These include NHS Talking Therapies for anxiety and depression, and social prescribing.

To ensure antidepressant drugs are made available to patients only where the benefits outweigh the potential harms, NHS England is encouraging the integrated care boards to address inappropriate antidepressant prescribing and to consider commissioning services for patients wishing to reduce or stop using antidepressants.