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Abiraterone

Asked by Danny BealesLabourDepartment of Health and Social CareTabled Answered 4 April 2025UIN 42127

The question

To ask the Secretary of State for Health and Social Care, whether he plans to take steps to allow doctors to prescribe Abiraterone.

Answered by Karin Smyth

The National Institute for Health and Care Excellence (NICE) is the independent body responsible for developing authoritative, evidence-based recommendations for the National Health Service on whether new, licenced medicines represent a clinically and cost-effective use of resources. The NHS in England is legally required to fund medicines recommended by the NICE for eligible patients in line with its recommendations.

The NICE has published guidance recommending abiraterone for the treatment of metastatic hormone-relapsed prostate cancer before chemotherapy is indicated and for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen. NHS England funds abiraterone for these indications of prostate cancer in line with the NICE’s recommendations, making it routinely available for clinicians to prescribe to eligible patients.

NHS England considered abiraterone as an off-label treatment for hormone sensitive, non-metastatic prostate cancer through its clinical policy development process in 2024/25. Through this process, NHS England confirmed that there was sufficient supporting evidence to support the routine commissioning of abiraterone in this indication and it was ranked in the highest priority level. However, NHS England could not identify the necessary recurrent funding to support commissioning of abiraterone, or any other treatments within the prioritisation round. Ministers are considering further advice on this issue.

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