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Estradiol

Asked by Sir Desmond SwayneConservativeDepartment of Health and Social CareTabled Answered 20 June 2025UIN 60408

The question

To ask the Secretary of State for Health and Social Care, what steps he is taking to ensure the provision of Estradot for women who react poorly to other HRT treatments.

Answered by Karin Smyth

There are over 70 hormone replacement therapy products, and the vast majority are in good supply. Currently, there are limited supplies of Estradot (estradiol) patches, which may be available to local pharmacies to order. We are working with the sole supplier of Estradot to expedite further resupplies where possible, however, supply issues are anticipated for the remainder of the year.

We have a range of well-established processes to manage supply issues when they arise, working closely with industry, the National Health Service, and the Medicines and Healthcare products Regulatory Agency to resolve issues as soon as possible. We have issued comprehensive management guidance to the NHS, which includes advice for prescribers to review patients individually if they are unable to tolerate suggested alternative products.

We have also issued Serious Shortage Protocols for Estradot 25, 50, 75, and 100 microgram/24 hour patches, allowing community pharmacists to supply the equivalent strength patch of an alternative brand without the need for a new prescription.

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