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Alzheimer's Disease: Drugs

Asked by Mr Andrew SnowdenConservativeDepartment of Health and Social CareTabled Answered 25 June 2025UIN 61301

The question

To ask the Secretary of State for Health and Social Care, if he will publish the cost-benefit modelling for the prescription of (a) donanemab and (b) lecanemab for patients with early-stage Alzheimer’s disease.

Answered by Karin Smyth

The National Institute for Health and Care Excellence has published the company’s evidence submission, which includes the company’s evidence on costs and benefits, and the external assessment group report, which assesses the company’s evidence submission as part of the papers that were considered by the independent Appraisal Committee. Information that is commercially confidential has been redacted.

The economic models themselves cannot be published because they contain commercially confidential information. The papers for lecanemab are available at the following link:

https://www.nice.org.uk/guidance/indevelopment/gid-ta11220/documents

In addition, the papers for donanemab are available at the following link:

https://www.nice.org.uk/guidance/indevelopment/gid-ta11221/documents.

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