Animal Experiments
The question
To ask the Secretary of State for Science, Innovation and Technology, what assessment she has made of the potential merits of animal-free tests such as the AcutoX for phasing out the LD50 test.
Answered by Kanishka Narayan
The strategy uses ‘baskets’ to group animal tests according to their readiness for replacement, based on maturity of potential alternative methods. These initial baskets will be refined in consultation with stakeholders, noting that two LD/LC50 tests are already in baskets 1 and 2 (botulinum potency and fish acute toxicity tests respectively) so are among the first targeted for phase-out. The Acutox test is a non-regulatory test and not yet validated for use in safety assessments. We will establish a new UK Centre for the Validation of Alternative Methods (UKCVAM) to accelerate alternative method validation and uptake for regulatory decision making.
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