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Blood Cancer: Medical Treatments

Asked by Paul DaviesLabourDepartment of Health and Social CareTabled Answered 20 January 2026UIN 105469

The question

To ask the Secretary of State for Health and Social Care, if he will take steps to ensure NHS patients with Mantle Cell Lymphoma will continue to be able to receive the CAR-T treatment Tecartus after it has exited the Cancer Drugs Fund.

Answered by Dr Zubir Ahmed

Decisions on whether new medicines should be routinely funded by the National Health Service in England are made by the National Institute for Health and Care Excellence (NICE) on the basis of an evaluation of their costs and benefits. NICE is currently re-evaluating brexucabtagene autoleucel (Tecartus) to determine whether it can be recommended for routine NHS use, taking into account real-world evidence generated through its use in the Cancer Drugs Fund. NICE has been unable to recommend the treatment in final draft guidance, which is available at the following link:

https://www.nice.org.uk/guidance/indevelopment/gid-ta11545/documents

This is because the available evidence does not suggest that brexucabtagene autoleucel is value for money in this population. Final guidance has not yet been published, and consultees have until 19 January to appeal NICE’s final draft recommendations.

In line with an arrangement between NHS England and the company, if NICE’s final guidance does not recommend use, patients who started treatment during the managed access period can continue their treatment.

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