Hypoxic-ischaemic Encephalopathy

There are robust, standardised criteria in place for diagnosing and treating hypoxic-ischaemic encephalopathy (HIE). Babies who meet these criteria are managed through regional networked pathways established by the British Association of Perinatal Medicine framework.

Treatment approaches are evidence-based and tailored to the severity of the condition. For infants diagnosed with moderate to severe HIE, therapeutic hypothermia is the recommended intervention and is typically initiated within the first six hours following birth.

To further support the diagnosis and treatment of hypoxic-ischaemic encephalopathy, research is underway to enhance our understanding of neonatal brain function following therapeutic cooling. Data relating to brain injury is also being incorporated into the Maternity Outcomes Signal System, which will trigger service-led critical safety checks, offering early insights into potential intrapartum care safety issues, and facilitating rapid intervention to reduce harm and improve outcomes for affected babies.